Targeting S. aureus biofilm formation to reduce the occurrence and the severity of flares-up in children with atopic dermatitis

These results showed that the SBT (Skin Barrier Therapy) confers to the dermo-cosmetic balm inhibition properties on S. aureus biofilm formation. A previously published study on the balm showed that after 6 months of application of this dermo-cosmetic balm in children with mild AD, 76% of patients did not relapse and the time-to-relapse increased (59 ± 11 days) compared to the emollient base (39 ± 12days). In addition, the severity of the relapses had decreased by -49% compared to -15% in the emollient base group. Therefore, these clinical results could be explained by the ability of the balm to prevent S. aureus from growing as a biofilm. In conclusion, the SBT demonstrates a great contribution in a dermo-cosmetic balm to reduce the flare-ups occurrence and severity in AD.